Details for gene set CL6926, DEFECTIVE BINDING OF RB1 MUTANTS TO E2F1,(E2F2, E2F3)[GSEA]

Table: GSEA Results Summary

Dataset	Chronic fatigue syndrome__20002-both_sexes-1482
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	CL6926, DEFECTIVE BINDING OF RB1 MUTANTS TO E2F1,(E2F2, E2F3)
Enrichment Score (ES)	0.81597275
Normalized Enrichment Score (NES)	1.3362142
Nominal p-value	0.029713115
FDR q-value	0.32978147
FWER p-Value	0.498

Fig 1: Enrichment plot: CL6926, DEFECTIVE BINDING OF RB1 MUTANTS TO E2F1,(E2F2, E2F3)
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CCNE1	209	2.370	0.7190	Yes
2	E2F2	2569	0.740	0.8160	Yes
3	CCNE2	11678	0.069	0.3309	No
4	CDK2	11895	0.065	0.3391	No
5	E2F1	14956	-0.000	0.1691	No
6	E2F3	15239	-0.000	0.1534	No
7	CDKN1C	15664	-0.000	0.1298	No
8	CCNA1	15758	-0.000	0.1247	No
9	CDK4	15820	-0.000	0.1213	No
10	RB1	15945	-0.000	0.1144	No

Fig 2: CL6926, DEFECTIVE BINDING OF RB1 MUTANTS TO E2F1,(E2F2, E2F3): Random ES distribution
Gene set null distribution of ES for CL6926, DEFECTIVE BINDING OF RB1 MUTANTS TO E2F1,(E2F2, E2F3)